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Article by ESTETICA.hr with Dr. Jelena Meštrović Štefekov, PhD, specialist in dermatovenereology.

Luxfaciem Skin Renew® is a science-based anti-ageing dermo-cosmetic line with the unique active ingredient CAP Peptide 5® and the innovative intelligent delivery system (SMART delivery system).

“CAP Peptide 5 is the product of years of work and is a unique peptide proven by numerous studies to repair damage and prevent premature skin ageing, protect collagen and help its regeneration, have antioxidant effects, increase skin elasticity and hydration.”

Why is CAP Peptide 5 unique? How did it happen?

The CSIC (Consejo Superior de Investigaciones Científicas) is Spain’s largest public institution dedicated to scientific and technical research and one of the most prominent in the European Research Area. It is attached to the Spanish Ministry of Science, Innovation and Universities. The CAP Peptide 5 peptide is a technology derived from this 20-year collaboration to treat a special and rare group of telomere diseases (telomeropathy), which lead to premature skin ageing. The peptides from which CAP Peptide 5 was derived are registered drugs for the treatment of telomeropathy.

By consensus of a multidisciplinary team of medical professionals in 2016 (dermatologists, oncologists, allergists, biologists and cosmetic doctors), in collaboration with the Spanish National Research Council (CSIC), it was decided to make CAP Peptide 5 available to everyone through dermo-cosmetics, due to its potent biological effects on ageing. This is how the Luxfaciem Skin Renew dermo-cosmetic line was born.

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LUXFACIEM SKIN RENEW® Treatment Line

Why is Luxfaciem Skin Renew so effective and how does it really work?

“Telomere shortening, collagen loss, oxidative stress and, ultimately, cell degradation are the main causes of skin ageing”

The aim of the research by a multidisciplinary team of scientists was to develop molecules that help protect and prolong the life of cells and tissues, and slow down the process of cellular stress (ageing) by acting on 5 main causes of ageing:

Conservation and lengthening of telomeres. Telomeres are the terminal parts of cell chromosomes. With each division and the formation of new cells, the telomere length gradually shortens, which eventually leads to cell breakdown and death. It is therefore not surprising that maintaining and lengthening telomeres is one of the main goals of anti-ageing strategies in general, not only in order to maintain the health and quality of the skin, but also of the whole organism. Studies show that CAP Peptide 5 maintains telomere length, which prolongs the life of skin cells. This is especially true for fibroblasts, the cells that produce collagen.
Increasing collagen levels while preserving its structure and architecture. In addition to protecting collagen-producing fibroblasts, CAP Peptide 5 demonstrates the ability to regenerate collagen fibres, protecting them from degradation while maintaining their structure and architecture, a cross-linking that gives strength and fullness to the skin.
Antioxidant action. Studies show that CAP Peptide 5 has a strong antioxidant effect, the so-called REDOX effect. It increases the levels of enzymes that protect cells from oxidative stress such as SOD and catalase. It reduces levels of inflammatory mediators such as IL-6 and IL-8. This reduces the accumulation of harmful active oxygen radicals, reduces inflammatory processes and protects cells from damage and decay.
Reducing the level of ageing biomarkers such as – ß-gala. Thanks to all these characteristics, CAP Peptide 5 leads to a reduction in the skin cell ageing process, as demonstrated by studies showing a decrease in the levels of the most important biomarker of skin ageing – ß-gala.
Improves skin hydration and elasticity. A 3-month application has been proven to increase skin elasticity and hydration and reduce the depth and thickness of wrinkles.

Furthermore, according to Dr. Meštrović Štefekov, for a particular active substance, including CAP Peptide 5, to be effective, a delivery system, delivery to the deepest layers of the skin, is very important, allowing the active ingredients to access the deep layers of the skin. It is in these layers, where CAP Peptide 5 acts, that we find the greatest amount of collagen. Luxfaciem Skin Renew features a new and unique SMART delivery system. The SMART delivery system facilitates the access of CAP Peptide 5 to the deep layers of the skin. This ensures the release of CAP Peptide 5 where it is needed most”- concludes Dr. Meštrović Štefekov.

The products are intended for all skin types.

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Day cream

Pleasant moisturising face cream with long-lasting and strong effect, which stimulates natural collagen production. It nourishes the skin, eliminates signs of ageing and reduces oxidative stress. Combines CAP Peptide 5, hyaluronic acid and other active ingredients that help regenerate cells and collagen deep in the skin, and vitamins and minerals necessary for optimal functioning of all skin cells. It reduces the expression of wrinkles, increases skin elasticity and radiance and reduces skin laxity. It is intended for mature skin due to its deep moisturising and regenerating properties. It does not irritate or dry out the skin.

Active ingredients: CAP Peptide 5, hyaluronic acid, antioxidants, polyphenols, vitamin E, moisturising active ingredients, sun filters, allantoin, trace elements, vegetable proteins, glycerine.

Eye contour

The action of the active ingredients CAP Peptide 5 and hyaluronic acid reduces the signs of skin ageing around the eyes such as fatigue, dehydration and relaxation, darker discolouration and puffiness. Reduces fine and expressive wrinkles, leaves skin smooth and glowing.

Active ingredients: CAP Peptide 5, hesperidin, hyaluronic acid, humectants, glycosaminoglycans, centella asiatica, soy protein, argireline, biological vitamins and antioxidants, microspheres with optical effect.

Serum

Intensive anti-ageing and repairing serum with a lifting effect. Combines high concentrations of CAP Peptide 5, hyaluronic acid and latest generation active ingredients. It has a strong antioxidant and anti-inflammatory effect. Promotes cell renewal and collagen production in the deep layers of the skin. The ability to deliver active ingredients deep into the skin provides an intense and long-lasting lifting effect, improves vitality and restores the skin’s radiance, protecting it from external factors.

Active ingredients: CAP Peptide 5, hexapeptide 10, antioxidants, hyaluronic acid, revitalising active ingredient, ingredients with lipid-forming protein, collagen, allantoin.

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Night cream

Rich, repairing, nourishing and regenerating night cream with a deep and long-lasting effect. Protects and promotes skin cell renewal. Consists of a combination of CAP Peptide 5, retinol and coenzyme Q10 and other nutrients and active ingredients that help the natural regeneration of collagen. It provides the skin with a high degree of hydration, giving it a soft, smooth and fresh appearance.

Active ingredients: CAP Peptide 5, antioxidants, coenzyme Q10, retinyl palmitate, kaolin, squalene, wheat and soy proteins.

Anti-spot cream

Relieves skin pigmentation irregularities (melasma) caused by excessive sun exposure, pregnancy or ageing. The whitening, detoxifying and antioxidant capacity of this preparation leads to a reduction of pigmentation expression, evens skin tone, restores and protects.

Active ingredients: CAP Peptide 5, acetyl glycyl beta-alanine, hexylresorcinol, plant extracts, Laminaria algae, bisabolol, allantoin, lecithin.

Body cream

Combination of nutrients and natural oils that prevent water loss, keep the skin hydrated and smooth, relieve itching. Contains natural proteins with repairing, lifting and antioxidant effects. It gives excellent results on dry and irritated skin, and after aggressive treatments. Due to its rapid and deep absorption into the skin, it creates a protective layer with a 24-hour effect. Relieves inflammation, irritation, itching and redness. Restores the comfort, softness, elasticity and vitality of healthy skin.

Active ingredients: CAP Peptide 5, rosehip oil, soybean glycine oil, rice germ oil, squalene, natural extracts, urea, allantoin.

You can find more information about Luxfaciem Skin Renew products HERE.

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